Food-grade Hyaluronic Acid Can Improve Joint Damage
| Material name | Food Grade of Hyaluronic Acid |
| Origin of material | Fermentation origin |
| Color and Appearance | White powder |
| Quality Standard | in house standard |
| Purity of the material | ＞95% |
| Moisture content | ≤10% (105°for 2hours) |
| Molecular weight | Around 1000 000 Dalton |
| Bulk density | ＞0.25g/ml as bulk density |
| Solubility | Water Soluble |
| Application | For skin and joint health |
| Shelf Life | 2 years from production date |
| Packing | Inner packing: Sealed Foil bag,1KG/Bag, 5KG/Bag |
| Outer packing: 10kg/Fiber drum, 27drums/pallet |
Hyaluronic acid, also known as hyaluronic acid, hyaluronic acid, and hyaluronic acid, is a glycosaminoglycan composed of disaccharide basic structure. Hyaluronic acid is widely found in connective, epithelial, and neural tissues. "Unlike most glycosaminoglycans, hyaluronic acid is not sulfated and is formed in the cell membrane rather than in Golgi bodies." Hyaluronic acid is one of the major components of the extracellular matrix.
Hyaluronic acid is an acidic mucopolysaccharide, which was first isolated from bovine vitreous in 1934 by Meyer et al., professor of ophthalmology at Columbia University. With its unique molecular structure and physical and chemical properties, hyaluronic acid shows a variety of important physiological functions in the body, such as lubrication of joints, regulation of vascular permeability, regulation of protein, water and electrolyte diffusion and circulation, and promotion of wound healing.
| Test Items | Specification | Test Results |
| Appearance | White Powder | White Powder |
| Glucuronic acid, % | ≥44.0 | 46.43 |
| Sodium Hyaluronate, % | ≥91.0% | 95.97% |
| Transparency (0.5% water Solution) | ≥99.0 | 100% |
| pH (0.5% water solution) | 6.8-8.0 | 6.69% |
| Limiting Viscosity, dl/g | Measured value | 16.69 |
| Molecular Weight, Da | Measured value | 0.96X106 |
| Loss on Drying, % | ≤10.0 | 7.81 |
| Residual on Ignition, % | ≤13% | 12.80 |
| Heavy Metal (as pb), ppm | ≤10 | ＜10 |
| Lead, mg/kg | ＜0.5 mg/kg | ＜0.5 mg/kg |
| Arsenic, mg/kg | ＜0.3 mg/kg | ＜0.3 mg/kg |
| Bacterial Count, cfu/g | ＜100 | Conform to the standard |
| Molds&Yeast, cfu/g | ＜100 | Conform to the standard |
| Staphylococcus aureus | Negative | Negative |
| Pseudomonas aeruginosa | Negative | Negative |
| Conclusion | Up to the standard | |
Actually, hyaluronic acid has distinction in different size, but how can we know the difference in hyaluronic acid molecular size? According to the definitions in the marketing, it can be divided into three classes hyaluronic acid. Please see the following picture:
1. Super molecular hyaluronic acid (molecular weight range 1 800 000 ~ 2200 000 Dalton), can only form a film on the surface of the skin, make the skin smooth and moist, and can block the invasion of foreign bacteria, dust, ultraviolet rays, protect the skin from damage.
2. Macromolecular hyaluronic acid: (molecular weight range 1 000 000 ~ 1 800 000 Dalton), basically not how to be absorbed by the skin, most stay in the stratum corneum, moisturizing the epidermal skin, skin feeling lubrication.
3. Small molecular hyaluronic acid (molecular weight range 400 000 ~ 1 000 000 Dalton) is a water-like hyaluronic acid molecule. It is mainly used for dermal injection of the whole face to supplement the lack of water in the dermis, repair the damaged skin, moisturize and rejuvenate the skin, and make up for the deficiency of large molecular and middle molecular hyaluronic acid.
1. In nutrition : hyaluronic acid is an intrinsic biological substance in the skin, and exogenous hyaluronic acid is a supplement to endogenous hyaluronic acid in the skin. Sodium hyaluronate can penetrate the epidermal layer of the skin, promote the supply of skin nutrients and the excretion of waste, so as to prevent skin aging and play a role in beauty and beauty. The maintenance of the skin is more important than other makeup, which has become the consciousness of modern people. Besides in the skin care hyaluronic acid has rich nutrition, it is also widely used in foods supplements. Such as solid drinking, capsules and so on.
2. In moisturizing : experiments showed that hyaluronic acid had the highest moisture absorption at low relative humidity (33%) and the lowest moisture absorption at relative humidity (75%) compared to these moisturizers. It is this unique property that is well adapted to the skin state under different environmental conditions. The moisturizing ability of hyaluronic acid is related to its quality, the higher the quality, the better the moisturizing performance. Hyaluronic acid is rarely used alone as a moisturizer and is often used in combination with other moisturizers.
3. In repair and prevention : hyaluronic acid can promote the regeneration of injured skin by promoting the proliferation and differentiation of epidermal cells and scavenging oxygen free radicals. The prior use of hyaluronic acid also has a certain preventive effect. In the most of time, we can combined hyaluronic acid with other ultraviolet light absorber to repair the damaged skin, so that our skin can be protected by double.
1. Background of Beyond Bioparma : Beyond Biopharma has been specialized produce hyaluronic acid for 10 years time. We have very mature production experiment and management system.
2. Advanced production equipment : We use electronic automatic control system to produce products, and at the same time there will be professional staff involved in production supervision. All equipment of production are tested by professional quality institution.
3. Professional production team : All our employees in all departments are trained by professional technology, and we regularly conduct training activities on operation safety, quality assurance and environmental hygiene.
4. Professional sales team : We have specialized sales team to answer our customers all questions in 24 hours. You can completely believe the ability of our sales teams.
Can I have small samples for testing purposes?
1. Free amount of samples: we can provide up to 50 gram of hyaluronic acid free samples for testing purpose. Please pay for the samples if you want more.
2. Freight cost: We usually send the samples via DHL. If you have DHL account, please let us know, we will send via your DHL account.
What are your ways of shipment:
We can ship both by air and be sea, we have necessary safety transportation documents for both air and sea shipment.
What is your standard packing ?
Our standarding packing is 1KG/Foil bag, and 10 foil bags put into one drum. Or we can do customized packing according to your requirements.
